Meanwhile, on Eyetube...

A former solution becomes an ugly problem, and a pediatric patient presents with a surprise membrane.

By Michael A. Klufas, MD

Hydrogel Explant Removal Following Partial Extrusion

Video submitted by Courtney Crawford, MD, and Chirag Shah, MD

Courtney Crawford, MD, and Chirag Shah, MD, present a difficult case of an intruding and extruding hydrogel buckle element with intraoperative scleral rupture. The Miragel hydrogel scleral buckle (Mira) was developed in the mid-1980s as an alterative to traditional silicone exoplants. It was touted as a new element to reduce the incidence of scleral erosion and to decrease postoperative infection by eluting antibiotics.1 These buried treasures from Boston are now being unpleasantly discovered by retina specialists as they undergo unanticipated hydrolytic degeneration.

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In a large series of 467 eyes at a single institution that underwent removal of these scleral buckles, the rate of retinal redetachment or intraoperative scleral perforation was 11%.2 Application of boric acid can shrink the hydrated exoplant, and use of cryocoagulation may facilitate removal, particularly of radial exoplants. To minimize scleral perforation, it is important to maximize exposure of the exoplant with a generous conjunctival peritomy, cut all sutures, and remove any encircling band prior to attempting removal of the Miragel element. The sclera should be inspected thoroughly and, in case of perforation, a patch graft applied. Given that the surface tension of air or gas is greater than that of silicone oil, placement of expansile gas with a pressure patch may be considered if continued leakage occurs.

1. Thompson JT, Chambers WA. Good ideas gone bad: the MIRAgel saga. Ophthalmology. 2016;123(1):5-6.

2. Crama N, Klevering BJ. The removal of hydrogel explants: an analysis of 467 consecutive cases. Ophthalmology. 2016;123(1):32-38.

Pediatric Terson Syndrome

Video submitted by Colin McCannel, MD, and Michael A. Klufas, MD

Dr. McCannel and I present a case of Terson syndrome in a 15-year-old child who presented with nonclearing vitreous hemorrhage. Upon removal of the vitreous hemorrhage, we noted an old sub–internal limiting membrane (ILM) hemorrhage with dehemoglobinized red blood cells. The ILM was peeled without staining, and the red blood cells were removed with a brush soft tip back flush.

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Terson syndrome is characterized by any intraocular hemorrhage (vitreous, sub-ILM, intraretinal, and/or subretinal) in association with intracranial hemorrhage. Pars plana vitrectomy (PPV) may be performed to remove vitreous hemorrhage, and other surgery techniques may be used to address other complications such as hemorrhagic macular cyst.

Cases of Terson syndrome treated with PPV but no ILM peel can develop a perimacular ring, which may occur secondary to detachment of the ILM.1,2 This may provide a scaffold for epiretinal membrane (ERM) to develop, and, if severe, proliferative vitreoretinopathy can occur. The goal of peeling the ILM in this case was to remove the retained red blood cells that could contribute to a secondary glaucoma and potentially prevent ERM formation that may lead to visual morbidity. Nevertheless, in any patient, particularly in pediatric patients, a risk-benefit analysis of each surgical step, such as ILM peel, should be carefully weighed. n

1. Sadeh AD, Lazar M, Loewenstein A. Macular ring in a patient with Terson’s syndrome. Acta Ophthalmol Scand. 1999;77(5):599-600.

2. Meier P, Schmitz F, Wiedemann P. Vitrectomy for pre-macular hemorrhagic cyst in children and young adults. Graefes Arch Clin Exp Ophthalmol. 2005;243(8):824-828.

Section Editor Michael A. Klufas, MD
• vitreoretinal surgeon, Mid Atlantic Retina, Philadelphia (beginning August 2016)
• retina chief,
• financial interest: consultant for Allergan


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About New Retina MD

New Retina MD delivers cutting-edge content to retina specialists in their first 15 years of practice. Each issue provides fresh insight from younger physicians plus established mentors on clinical and nonclinical issues affecting ophthalmologists in the earlier stages of their careers. NRMD features surgical pearls, clinical research endeavors, practice management, medical reimbursement and policy, continuing educational requirements, financial planning, innovations, and more.